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In granulosa cells of women with endometriosis, elevated lipid peroxidation markers such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) have been observed, accompanied by decreased glutathione (GSH) and glutathione peroxidase 4 (GPx4), key inhibitors of ferroptosis (32)
Figure S14 indicates no significant difference in body weight changes across these treatment groups
Thus, identifying CVD-associated variants may inform precision medicine efforts to prevent and treat CVD 5,6
DAPK1 promotes extrasynaptic GluN2B phosphorylation and striatal spine instability in the YAC128 mouse model of Huntington disease
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